Ten tame eland (Taurorragus oryx), four kudu (Tragelaphus strepsiceros), two gemsbok (Oryx gazella), six springbok (Antidorcas marsupialis) and 33 domestic goats were drenched by stomach tube with extracts of the poisonous plant gifblaar (Dichapetalum cymosum) (Hooker) Engler and PrantI. The lesions caused by gifblaar are descriptionbed. Keywords: Adrenal haemorrhages, Blockage of Krebs cycle, Blood-stained bile, Cardiac arrest, Haemorrhages of gall bladder, Histopathological changes, Monofluoroacetate, Oedema, Pancreas, Periportal area of liver, Petechiae in urinary bladder, Pulmonary valves and Suspension.