The drought-tolerant tree species Colophospermum mopane is focussed at for an assessment of the impact of water stress, as well as for the specific adaptation potential of the species. Three differing sites ('Forest', 'Shrubs' and 'Swamp') under three different seasonal situations (advanced dry season, drought and early rain season), in the mopane woodland of north-eastern Namibia were studied. Keywords: Mopane woodland, C. mopane, Site-species matching, Adaptation, Drought, Zambezi region.