The idea of degradation of arid and semi-arid lands, often termed desertification in its irreversible form, due to human impact and/or climatic change has been much debated since the mid-1970s. From the time of the United Nation's Conference On Desertification in Nairobi, 1976, certain areas of northern Burkina Faso have been pointed out as examples of severe desertification. Several studies demonstrated that revitalization of a series of E-W oriented fossille dunes in the Oudalan province was ongoing. The present study includes an analysis of the trends of vegetation development in the region, covering the period 1955 to 1994, with emphasis on the fossile dunes. It is demonstrated that desertification and revitalization of dunes were phenomena associated with the period between the early 1970s and the mid-1980s, and that the decline in vegetation cover on the dunes seems to have been reversed in recent years. The analysis is based upon time series of aerial photos and satellite images, field studies of vegetation, interviews with local people and review of relevant literature. Keywords: Desertification, Land degradation, Vegetation change, Remote sensing, Burkina Faso.