Abstract: The Cape Floristic Region (CFR) (Cape Floristic Kingdom) is currently narrowly delimited to include only the relatively mesic Cape fold mountains and adjacent intermontane valleys and coastal plains. We evaluate the floristic support for expanding the delimitation to include the whole winter-rainfall area (arid and mesic climates) into a Greater CFR. Keywords: Biogeographical regions, Cape flora, clustering analyses, endemism, floristic elements, minimum spanning trees, phytochoria, South Africa, Succulent Karoo.