The Ju/’hoansi San of the Nyae Nyae Conservancy (NNC) in the Otjozondjupa Region of Namibia have been involved in work related to climate change adaptation and the diversification of livelihood strategies for nearly four decades. Anthropologists have been working with the Ju/’hoansi since 1951. Since the 1980s, anthropologists and development workers have promoted small-scale community-based development that includes agriculture, livestock, forestry, and income generation activities. The Ju/’hoansi, who currently are suffering from a severe drought (2019–2020), are employing a variety of adaptive strategies to cope with climate change and now, the most recent COVID-19 pandemic and its related crises. These strategies are assessed in light of the United Nations Sustainable Development Goals (SDGs). Contemporary challenges facing the Ju/’hoansi include incursions of pastoralists who are competing for grazing and water, the presence of large numbers of elephants (Loxodonta africana), which require the construction of expensive water point protection facilities, and hunger is on the increase in some of the drought-affected villages, in spite of government and NGO-sponsored commodity and cash provision programs. The expansion of capacity building efforts targeting people in the Nyae Nyae communities is clearly needed. At present, the Ju/’hoansi, along with their neighbors, are seeking to address food security, nutrition, and health issues and to promote climate change and emergent crises-responsive resilient livelihoods.