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Lions are the most-traded wildcat in the world, and the only big cat whose commercial trade is permitted under CITES, the international wildlife trade agreement. Lion body parts, including bones, skins, claws and teeth, trophies and live individuals are traded across the world, both legally and illegally. South Africa stands out as a hotspot for the trade due to the flourishing captive lion industry, which also supplies body parts and engages in canned hunting.

Endangered African painted dogs are at the risk of local extinction due to poachers hunting other wildlife at Zimbabwe's Hwange National Park. The painted dogs are victims of rampant poaching by local and international syndicates hunting for wildlife such as buffaloes and elephants. Although poachers have no interest in painted dogs themselves, they become victims of snares or poisoned water sources meant for other game. The destruction of their habitants is also cited as one of the reasons why the painted dogs face extinction. "It’s not about the painted dogs only.

For the past three decades Namibia has adopted conservation approaches that have expanded the range and increased the population sizes of many wildlife species, including black rhinoceros, elephants, and large carnivores. Wildlife recoveries have been particularly noteworthy within the communal areas of Namibia, attributed to the emergence of communal conservancies since 1996. Namibia's progressive legislation has allowed people living with wildlife to benefit from these natural resources, resulting in community stewardship, goodwill, and support for nature conservation.