The unusual disjunct distribution of the yellow-flowered, radiate, Northern Cape endemic Emilia hantamensis J.C.Manning & Goldblatt, relative to the other Emilia species in southern Africa, prompted investigation into its phylogenetic position and relationships. Phylogenies based on the ITS and trnL-trnF regions reveal that it is not a member of the genus Emilia but belongs in a well-supported clade with Bolandia, a genus comprising five species mainly from the Western and Northern Cape, and the monotypic genera Stilpnogyne and Mesogramma. It is placed sister to Bolandia and its cypselas match those of Bolandia in shape, colour and indumentum, except for a distinct ridge of hairs on the inner rib of the ray cypselas. It is further distinguished from Bolandia by its annual habit and conical disc floret style apices and obtuse to rounded ray floret style apices. It is recognised and described here as a new monotypic genus, Bertilia Cron with the single species B. hantamensis (J.C.Manning & Goldblatt) Cron. Keywords: Emilia hantamensis, Molecular phylogeny, Northern Cape endemic, Systematics.