This inside story forms part of the CDKN Knowledge for Change series, which reflects on the common challenges, lessons and successes CDKN and its partners have encountered in facilitating evidence-based decision-making to accelerate climate action. The aim of this work is to better understand how knowledge and evidence on climate change can inform and translate into policy and implementation. This reflection process has investigated different tools and approaches for enhancing the use of knowledge in decision-making, the barriers encountered in facilitating change, and lessons useful for others who navigate similar challenges.