The southern most basement inlier within the Damara Orogen, the Rehoboth Basement Inlier, covers an area of approximately 150002 km with its northernmost outcrops situated about 70 km south of Windhoek, the capital of Namibia. The aim of this study is to elucidate the geological history of the inlier, which is composed of a succession of metavolcano-sedimentary acid and basic rock formations which are intruded by granitoid as well as basic magmas. Sm-Nd and U-Pb analyses of granitoids, amphibolites and basic dykes show that the major part of the Rehoboth crust formed during the early Proterozoic between 2.6 and 1.8 Ga as an accretionary belt on the northwest side of the Archaean Kalahari Craton and possibly equivalent to the younger parts of the South African and Zimbabwean Limpopo Province. During the early stages of this crustal evolution the freshly formed crust must also have been readily reworked by various stages of erosional, metamorphic and anatectic processes in order to be present today as a metamorphosed volcano sedimentary sequence, including the lithologies from the Mooirivier Complex at its base to the Billstein Formation at its top. This theory of early reworking of the originally formed crust is supported by the occurrence of granitic pebbles and boulders in various formations of the Rehoboth Sequence.