This paper presents major element, trace element and radiogenic isotope data for selected A-type granites (sensu-lato) from the Pan-African Damara belt, Namibia. The granites studied include those from Sorris-Sorris, Dachsberg, Horebis River, and a Salem-type intrusion from the Swakopmund region. The first three of these exhibit high FeOt /(FeOt + MgO) and high TiO2 /MgO ratios, characteristics of A-type granites, and all four intrusions display distinctive enrichments in the high field strength elements (e.g. Nb, Y, Zr). However, only a small number of the high-silica (>73 wt % SiO2 ) samples exhibit low CaO and low Al2 O3 , characteristics of many A-type granites world-wide. Magmatic temperatures inferred from the zirconium solubility model (typically in excess of 780°C) are higher than those of broadly contemporaneous S-type granites, although elevated F abundances, characteristic of many A-type granites, will result in a higher zirconium solubility at a given temperature. Most of the A-type granites studied here exhibit initial Sr and Nd isotope ratios similar to Damara calc-alkaline diorites and granodiorites. Their major and trace element characteristics are consistent with derivation by partial melting of felsic calc-alkaline source rocks, but less silicic examples require a contribution from more mafic material. On the basis of results from recently published melting experiments on felsic calc-alkaline sources, mid-crustal low-pressure (4-6 kbar) rather than high-pressure (10 kbar) melting is inferred. The generation of intraplate trace element signatures (high HFS/LILE ratios) by partial melting of calc-alkaline source rocks requires enhanced HFS element solubility in the magmas. This could reflect higher magmatic temperatures which promotes dissolution of HFS-enriched minor phases and/or high F activity in the magma. The data for these A-type granites preclude any significant involvement of old metasedimentary material in their genesis.