Carnivore populations face threats from increasing human populations and rapidly diminishing, suitable habitat. Large carnivores such as African lions (Panthera leo) commonly attack livestock on lands adjacent to protected areas. This can lead to human-wildlife conflict (HWC) events that result in retaliatory lion killings. Conflict is a primary driver of wild lion population declines which are estimated to have decreased by 43% in the last 20 years. Etosha National Park (ENP) in Namibia is an IUCN designated Lion Conservation Unit and is home to the country's largest surviving and only stable lion population. Lions cross onto farmlands bordering ENP leading to 40 to 50 lions reported as killed from HWC annually. Park officials suspect that HWC events are further increasing each year. Recent social, political and land use changes may be altering HWC reporting in regional offices, causing an artificial decrease in documented HWC events. Combining spatial-statistical modeling techniques can accurately predict future HWC and lion mortality risk by accounting for both present lion population distribution and past conflict hotspot locations around a park. The "conflict risk maps" resulting from these analyses will highlight high priority areas to focus future conservation actions and conflict mitigation strategies, serving to better understand and conserve Etosha and its lions.