The Rössing granite-hosted uranium deposit in the Central Zone of the Pan-African Damara Orogen, Namibia, is situated in the "SJ area" to the south of the Rössing Dome. The coincidence of a number of features in this area suggests that mineralisation is closely linked to late-kinematic evolution of the Rössing Dome. These features include: (1) the rotation of the dome's long axis (trend of 017°), relative to the regional F3 trend of 042°; (2) southward dome impingement, concomitant with dome rotation, producing a wedge-shaped zone of alkali-leucogranites, within which uranium mineralisation is transgressive with respect to granites and their host lithologies; uranium mineralisation and a high fluid flux are also confined to this arcuate zone to the south and south-east of the dome core and (3) fault modeling that indicates that the SJ area underwent late-D3 to D4 brittle–ductile deformation, producing a dense fault network that was exploited by leucogranites. Keywords: Leucogranite, Uranium, Mineralization, Late-kinematic, Damara Orogen, Namibia.