Four previously unrecognized neotectonic fault scarps in southwest Namibia are described. These relatively straight, simple but segmented structures are 16–80 km long and have measured vertical separations of 0.7–10.2 m. We estimate that each is capable of producing earthquakes of Mw 6.4 or greater, indicating that large earthquakes may occur despite limited cumulative displacement. There is strong evidence that some of these scarps were formed by repeated earthquakes. Comparison with aeromagnetic and geological maps reveal that the normal faults reactivate major crustal weaknesses that are orientated north-south and northwest-southeast and perpendicular to the local gravitational potential energy gradient. The presence of these structures in an area with a limited record of instrumental seismicity suggests that the Mmax of this region may be much larger than generally assumed. They highlight the necessity of incorporating information from fault studies into probabilistic seismic hazard assessments in this region, in a similar way to other stable continental regions such as Australia. The fact that such major structures have gone hitherto unrecorded suggests significant further research is needed to characterize these sources of hazard. The identification of an apparent cluster of large magnitude neotectonic earthquakes in the area may be related to the exceptional preservation potential of scarps rather than indicating an area of comparatively rapid deformation. If this interpretation is correct, then these scarps represent an important indication of the potential seismic hazard across the region, and the occurrence of infrequent large-magnitude seismicity on similar structures should be considered throughout southwestern Africa.